H1N1 INFLUENZA A VIRUS (SWINE FLU)

Blog Last Updated June 11, 2009


LEVEL VI (June 11, 2009)

 The World Health Organization told its member nations it was declaring a swine flu pandemic Thursday (June 11) — the first global flu epidemic in 41 years — as infections climbed in the United States, Europe, Australia, South America and elsewhere.

In a statement sent to member countries, WHO said it decided to raise the pandemic warning level from phase 5 to 6 — its highest alert — after holding an emergency meeting on swine flu with its experts.

The long-awaited pandemic decision is scientific confirmation that a new flu virus has emerged and is quickly circling the globe. It will trigger drugmakers to speed up production of a swine flu vaccine and prompt governments to devote more money toward efforts to contain the virus.

"At this early stage, the pandemic can be characterized globally as being moderate in severity," WHO said in the statement, urging nations not to close borders or restrict travel and trade. "(We) remain in close dialogue with influenza vaccine manufacturers."

On Wednesday, WHO said 74 countries had reported nearly 27,737 cases of swine flu, including 141 deaths.

The agency has stressed that most cases are mild and require no treatment, but the fear is that a rash of new infections could overwhelm hospitals and health authorities — especially in poorer countries.

Still, about half of the people who have died from swine flu were previously young and healthy — people who are not usually susceptible to flu.

Swine flu is also continuing to spread during the start of summer in the northern hemisphere. Normally, flu viruses disappear with warm weather, but swine flu is proving to be resilient.

The last pandemic — the Hong Kong flu of 1968 — killed about 1 million people. Ordinary flu kills about 250,000 to 500,000 people each year.

Fear has already gripped Argentina, where thousands of people worried about swine flu flooded into hospitals this week, bringing emergency health services in the capital of Buenos Aires to the brink of collapse. Last month, a bus arriving in Argentina from Chile was stoned by people who thought a passenger on it had swine flu. Chile has the most swine flu cases in South America.

In Hong Kong on Thursday, the government ordered all kindergartens and primary schools closed for two weeks after a dozen students tested positive for swine flu — a move that some flu experts would consider an overreaction.

In the United States, where there have been more than 13,000 cases and at least 27 deaths from swine flu, officials at the U.S. Centers for Disease Control and Prevention said the move would not change how the U.S. tackled swine flu.

"Our actions in the past month have been as if there was a pandemic in this country," Glen Nowak, a CDC spokesman, said Thursday.

The U.S. government has already taken steps like increasing availability of flu-fighting medicines and authorizing $1 billion for the development of a new vaccine against the novel virus. In addition, new cases seem to be declining in many parts of the country, U.S. health officials say, as North America moves out of its traditional winter flu season.

Still, Osterholm said the declaration was a wake-up call for the world.

"I think a lot of people think we're done with swine flu, but you can't fall asleep at the wheel," he said. "We don't know what's going to happen in the next 6 to 12 months."

PLEASE KEEP READING, AS IT IS JUST AS IMPORTANT NOW AS WHEN IT WAS WRITTEN MAY 27!

May 27, 2009

Everything we've seen to date leaves us with the understanding that we need to remain vigilant. We cannot let up on this. It's important that people understand that there's shared responsibility, that people need to continue to wash their hands, cover their coughs, and, most importantly, when they are sick, not go to school, not go to work when they are sick. Those measures can help reduce the spread in communities and keep people protected.

The CDC does expect to see more school outbreaks.  They do expect to see more clusters around the country. They do expect to see more transmission and they do expect to see disease in all states.

For the CDC to move or for W.H.O. to move from a level five or level six, they will look to see is there sustained transmission of this virus in more than one W.H.O. region?  With the number of cases in other countries, the CDC would be surprised if we don't get to a level six.  But we are not there yet and W.H.O. has not made that move.

As the flu season starts in the southern hemisphere, what takes place there is going to be incredibly important, how does the virus compete with other viruses that are circulating in the community, does it change, does it mutate?  If so, in what way?  Does it develop resistance?

For additional information on Press Conference, May 6, 2009, click below:

http://www.cdc.gov/media/transcripts/2009/t090506.htm


For Our Students, Faculty, and Staff

As you may know, the World Health Organization has raised the level of alert to LEVEL SIX. Since then, the University’s actions are consistent with those measures, such as activating its pandemic influenza response plan, which was developed three years ago in response to the potential outbreak of avian flu.

There is no imminent danger to the health of the University community at this time. However, the situation is evolving and University officials are closely monitoring developments. Do your part by keeping calm, informed, and practicing personal hygiene.

Faculty, staff, or students who experience flu-like symptoms are encouraged to use their sick days and stay home from work to keep others from getting sick. Flu-like symptoms are defined as a fever of 100 F (37.8 C) or higher, runny nose, cough, sore throat, and respiratory congestion.

Faculty, staff, and students, who experience flu-like symptoms and have traveled to an area experiencing an outbreak of flu in the last seven days or have been exposed to someone with the flu in the last seven days, are urged to seek treatment from their regular health care provider.



WHO, instead of calling it swine flu, will label it by its technical scientific name H1N1 influenza A (April 30, 2009).



Interim CDC Guidance for Colleges, Universities, and Post-secondary Educational Institutions in Response to Human Infections with Novel Influenza A (H1N1) Virus (May 9, 2009)

These recommendations are based on current information and are subject to change based on ongoing surveillance and risk assessment.

For the purpose of this guidance, the term “university” is used to refer to institutions of higher learning (e.g. universities and colleges) and other post-secondary educational institutions.

Background

This document provides interim guidance specific for universities during the outbreak of novel influenza A (H1N1) virus on suggested means to reduce the spread of influenza in universities and their communities. These recommendations are based on the recognition of sustained human to human transmission of this new virus, which has spread across much of the United States, and information which suggests most cases of illness from this virus are similar in severity to seasonal influenza. However, recommendations may need to be revised as more information becomes available.

Interim Recommendations:

  • CDC is not currently recommending that colleges, universities, or post-secondary educational institutions cancel or dismiss classes or other large gatherings.
  • If confirmed cases of novel influenza A (H1N1) virus infection or a large number of cases of influenza like illness (ILI) (i.e. fever with either cough or sore throat) occur among students, faculty, or staff or in the community, university officials should consult with state and local health officials regarding an appropriate response.
  • Because the spread of novel influenza A (H1N1) within a health professions school may pose special concerns, school administrators are strongly encouraged to contact their state and local public health authorities if they suspect that cases of ILI are present on their campuses.
  • Students, faculty or staff who live either on or off campus and who have ILI should self-isolate (i.e., stay away from others) in their dorm room or home for 7 days after the onset of illness or at least 24 hours after symptoms have resolved, whichever is longer.[Student Health Services strongly endorses this recommendation.]
  • If possible, persons with ILI who wish to seek medical care should contact their health care provider or university health services [901.678.2287] to report illness by telephone or other remote means before seeking care. Universities should assure that all students, faculty, and staff receive messages about what they should do if they become ill with ILI, including reporting ILI to university health services. [If faculty, staff, or student has been diagnosed with H1N1 Flu, please notify Student Health Services at 901.678.2287 as soon as possible.]
  • If persons with ILI must leave their home or dorm room (for example, to seek medical care or other necessities) they should cover their nose and mouth when coughing or sneezing. A surgical loose-fitting mask can be helpful for persons who have access to these, but a tissue or other covering is appropriate as well. (See http://www.cdc.gov/h1n1flu/guidance_homecare.htm Interim Guidance for H1N1 Flu (Swine Flu): Taking Care of a Sick Person in Your Home).
  • Roommates, household members, or those caring for an ill person should follow guidance developed for caring for sick persons at home. (See http://www.cdc.gov/h1n1flu/guidance_homecare.htm Interim Guidance for H1N1 Flu (Swine Flu): Taking Care of a Sick Person in Your Home).
  • Persons who are at high risk of complications from novel influenza A (H1N1) infection (for example, persons with certain chronic medical conditions, children less than 5 years, persons 65 years or older, and pregnant women) should consider their risk of exposure to novel influenza if they attend public gatherings in communities where novel influenza A virus is circulating. In communities with several reported cases of novel influenza A (H1N1) virus infection, persons who are at risk of complications from influenza should consider staying away from public gatherings.

Large gatherings

On the basis of what is currently known about the ongoing spread of novel influenza A (H1N1) and, as a means to prevent the further spread of disease on and off campus, universities should encourage persons with ILI to stay home and away from large gatherings. Persons who are sick should be instructed to limit their contact with other people as much as possible and to stay home for 7 days after their symptoms begin or until they have been symptom-free for 24 hours, whichever is longer. In addition, they should be reminded to use appropriate respiratory and hand hygiene. Gatherings may include graduations and commencement activities, concerts, sporting events, and other gatherings where close contact is likely between a large number of attendees.

Large university and other public gatherings offer a good opportunity for officials and event organizers to deliver key educational messages about measures attendees can take to help protect themselves and their family members from novel influenza A (H1N1) infection, including active promotion of good hygiene practices. [Monitor the University's Student Health Services Blog: www.uofmshs.typepad.com.]

 



1.   What is H1N1 Influenza A (Swine Flu)?

Swine flu is a respiratory disease affecting pigs that is caused by type A influenza virus. Swine influenza viruses may circulate among swine throughout the year, but most outbreaks occur during the late fall and winter months, similar to influenza outbreaks in humans. It causes high levels of illness but low death rates in pigs.

What is unusual about the present strain?

The new strain is a hybrid of swine, human and avian flu viruses and the US Centers for Disease Control and Prevention (CDC) says it can spread from human to human but the level of virulence is not yet clear.

2.   Does Swine Flu affect humans?

Swine flu viruses that cause disease in pigs very rarely affect humans. However, sporadic human infections with swine flu have occurred. Most commonly, these cases occur in persons with direct exposure to pigs but there have also be documented cases of human-to-human spread of swine flu.

3.   How does Swine Flu Spread to humans?

Swine flu spread to humans mainly through contact with infected pigs, which shed the virus in their saliva, nasal secretions and feces. Limited human-to-human transmission can also occur in the same way as seasonal flu occurs in people.

4.   Can people catch Swine Flu from eating pork?

There is currently no evidence to suggest that swine flu can be transmitted to humans from eating pork or pork products that have been thoroughly cooked.

5.   What are the symptoms of Swine Flu in humans?

The symptoms of swine flu in people are expected to be similar to the symptoms of regular human seasonal influenza. An early symptom is fever, and this is followed by cough, sore throat, runny nose and sometimes breathlessness a few days later.

6.   How can human infections with swine flu be diagnosed?

To diagnose swine flu, a respiratory specimen would generally need to be collected within the first 4 to 5 days of the illness (when an infected person is most likely to be shedding the virus). However, some persons, especially children may shed the virus for 10 days or longer.

7.  What medications are available to treat swine flu infections in humans?

There are four different antiviral drugs for the treatment of influenza: amantadine, rimantadine, oseltamivir, and zanamivir. While most swine flu viruses have been susceptible to all four drugs, the most recent swine flu viruses isolated from humans are resistant to amantadine and rimantadine. At this time the US CDC recommends the use of oseltamivir (Tamiflu) or zanamivir (Relenza) for treatment and/or prevention of infection with swine flu viruses.

8.  Is it safe to visit countries with cases of Swine Flu and will I be quarantined when I return? What travel precautions should I take?

The State Department recommends that "U.S. citizens avoid all nonessential travel to Mexico at this time." Some tour operators and airlines across the globe have canceled flights and holiday packages to sunshine destinations like Cancun and Cozumel. To be sure, contact your operator or airline. No quarantine situation has been advised by the World Health Organization (WHO) for swine flu at this time (April 29, 2009). If you travel to areas which have cases of swine flu, you should take note of the following measures to minimize your risk of acquiring swine flu:

*Avoid contact with persons with symptoms of influenza.

*Avoid crowded areas and maintain good ventilation. Stay at least six feet away from individuals.

*Observe good personal and environmental hygiene. Wash hands thoroughly with soap and water frequently and when they are contaminated by respiratory secretions e.g. after sneezing and coughing.Swine flu cough pict

*Maintain good body resistance through a balanced diet, regular exercise, having adequate rest, reducing stress and not smoking.

9.   What should I do if I suspect I have swine flu after returning from a country that has cases of swine flu?

You should consult your doctor as soon as possible and inform your doctor if you have symptoms of swine flu and had recently traveled to area which have cases of swine flu.

10.             What should I do if I fall ill overseas?

You should consult a local doctor as soon as possible and refrain from traveling until you are certified fit by the doctor.

11.             Does influenza vaccination help prevent Swine Flu?

There is no vaccine to protect humans from swine flu. The seasonal influenza vaccine is unlikely to protect against H1N1 swine flu viruses.

12.             What Can I Do to Stay Healthy?

There are everyday actions people can take to stay healthy.

Wash your hands often with soap and water, especially after you cough or sneeze. Alcohol-based hands cleaners are also effective.Wash hands picture


Avoid touching your eyes, nose or mouth. Germs spread that way.

Try to avoid close contact with sick people.

·        Influenza is thought to spread mainly person-to-person through coughing or sneezing of infected people.

 

·        If you get sick, CDC recommends that you stay home from work or school and limit contact with others to keep from infecting them.

Stay home photo

Q: Should we be worried about Swine Flu?

A: No - but we should take sensible precautions and stay informed. The World Health Organization has warned that the outbreak has "pandemic potential" and countries have been advised to step up surveillance and preparation in case the infection spreads rapidly.

Q: Does swine flu pose a more serious threat to pregnant women?

A: All viruses are potentially dangerous to pregnant women as their immune systems are under extra strain - but they should be fine if they eat well and keep up essential minerals.

Q: How long does the flu virus survive on surfaces?

A: The flu virus survives for roughly 24 hours on hard surfaces, two hours on soft surfaces.

Q: What is a pandemic?

A: If the flu spreads over a wide geographic area and affects a large proportion of the population it goes beyond an epidemic and becomes a pandemic.

According to the Health Protection Agency, an influenza pandemic is defined as a new or novel influenza virus that spreads easily between humans.

When new influenza viruses are introduced into the environment, humans do not have any natural immunity to protect against them.

Therefore, there is a risk that that new influenza viruses could develop into a pandemic, if the virus passes easily from human-to-human.

Q: Have humans been infected with swine flu in the past?

A: Cases of swine flu in humans usually occur after a history of exposure to pigs. For example, direct or close contact with infected pigs.

Cases of person-to-person transmission have been previously reported but are rare.

There have been no cases identified in the UK for at least 10 years.

A single case of swine flu was reported in November 2008 in Spain. The person only had mild symptoms.

May 07, 2009

Cases of H1N1 Flu Virus (Human Swine Flu) in U.S and Canada

(1) To follow H1N1 Flu Virus A (Human Swine Flu) in U.S., click below:

http://www.cdc.gov/h1n1flu/update.htm


(2) For Canada, click below:

http://www.phac-aspc.gc.ca/alert-alerte/swine-porcine/surveillance-eng.php


May 05, 2009

What Pregnant Women Should Know About H1N1 (formerly called swine flu) Virus

What Pregnant Women Should Know About H1N1 (formerly called swine flu) Virus


What if I get this new virus and I am pregnant?

Photo of expecting motherWe don’t know if this virus will cause pregnant women to have a greater chance of getting sick or have serious problems. We also do not know how this virus will affect the baby.

We do know that pregnant women are more likely to get sick than others and have more serious problems with seasonal flu. These problems may include early labor or severe pneumonia. We don’t know if this virus will do the same, but it should be taken very seriously.

What can I do to protect myself, my baby and my family?

Take these everyday steps to help prevent the spread of germs and protect your health:

  • Cover your nose and mouth with a tissue when you cough or sneeze, or sneeze into your sleeve. Throw the tissue in the trash after you use it.
  • Wash your hands often with soap and warm water, especially after you cough or sneeze. Alcohol-based gel hand cleaners are also good to use.*
  • Avoid touching your eyes, nose or mouth. Germs spread this way.
  • Try to avoid close contact with sick people. (If you are pregnant and you live or have close contact with someone who has H1N1 flu, talk to your doctor about medicines to prevent flu.)
  • Have a plan to care for sick family members.
  • Stock up on household, health, and emergency supplies, such as water, Tylenol®, non-perishable foods.

To read more of this article: http://www.cdc.gov/h1n1flu/guidance/pregnant.htm

May 01, 2009

YOUR PERSONAL PLAN

As with any potential emergency, it is good to have a plan for yourself and your family. Authorities recommend having at least 7 days’ worth of water and non-perishable food on hand so that you could “shelter in place,” if necessary. (http://www.pandemicflu.gov/plan/individual/checklist.html)

Because a pandemic, if it ever comes, is likely to disrupt the normal routines of all commerce, transportation, banking, and health care as well as schools, churches and other places, you should not assume that public or private agencies will be able to come to your rescue. 

HISTORY OF PANDEMICS

History of Pandemics

Once a disease becomes highly transmissible and spreads efficiently and rapidly to humans around the world, it is considered a pandemic.  There have been 10 recorded pandemics over the past 300 years, three of which occurred in the last century: (http://www.cdc.gov/flu)

  • In 1918-1919, the “Spanish Flu” or H1N1 sickened an estimated 20-40% of the world’s population.  Millions of people died; 500,000 in the U.S.  It spread rapidly; many died within days of infection.  The attack rate and mortality was highest among adults 20-50 years old, although the reasons for this are uncertain.


  • In 1957-58, the “Asian Flu” or H2N2 caused an estimated 2 million deaths worldwide, including about 70,000 in the U.S.  Infection rates where highest among school children, young adults and pregnant women; the death rate was highest among the elderly.  A second wave developed in 1958.

  • In 1968-69, the “Hong Kong Flu” or H3N2 caused nearly a million deaths around the world and 34,000 in the U.S.  Victims over age 65 were most likely to die.  This virus returned in 1970 and 1972 and still circulates today. 

April 30, 2009

CLEANING AND DISINFECTING

KEEPING YOUR LIVING AND WORK AREA SAFE with BLEACH AND ALCOHOL

(1) First make sure you or everybody in the contact area is Not allergic to Bleach. You can wear a mask, eye protection and gloves to further protect yourself.

(2) Mix one (1) teaspoon and up to one (1) tablespoon of Bleach to a gallon of water.

(3) Put the mixture in a spray bottle and lightly spray the air or environment that has been exposed to the illness. Keep in mind that you are working with bleach so be careful when spraying not to spray too much on a surface that can bleach out in color, such as furniture or carpet or bedding. A light mist usually will not change the color but it is always best to take precautionary steps where needed.

(4) Keep in mind that you are out to kill a little tiny living virus and it only takes a little tiny dose of bleach water to kill such a small living thing but there may be millions of the little virus beings in the air or room so complete coverage is still advised.

(5) Sanitize things you touch frequently such as doorknobs and light switches, garage door openers, telephones, keyboards, etc. Walk through your home or office areas and see what you frequently touch without thinking.

(6) Also, 70 percent alcohol can be used. With an alcohol wipe with 70 percent alcohol you can attack any of the surfaces in your office or home.

And exactly which products should you buy to wipe out any flu virus?

(7) Brand names are good because in particular they are verifiably and reproducibly good at killing germs. That's one thing you can count on.

(8) The best sanitizer for hands is 62 percent alcohol solutions. Put a quarter-sized dollop onto your palm - enough to keep you rubbing for about 30 seconds between the fingers, under the nails, over the tops of your hands, and under your palms.

CDC Releases Guidance for Reducing People's Exposure to Swine Flu (April 27)

Recommendations

When Human Infection with Swine Influenza A (H1N1) Virus is Confirmed in a Community

Strongly Recommend Home Isolation of Cases:


  • Persons who develop influenza-like-illness (ILI) (fever with either cough or sore throat) should be strongly encouraged to self-isolate in their home for 7 days after the onset of illness or at least 24 hours after symptoms have resolved, whichever is longer. Persons who experience ILI and wish to seek medical care should contact their health care providers to report illness (by telephone or other remote means) before seeking care at a clinic, physician’s office, or hospital. Persons who have difficulty breathing or shortness of breath or are believed to be severely ill should seek immediate medical attention.
  • If ill persons must go into the community (e.g., to seek medical care) they should wear a face mask to reduce the risk of spreading the virus in the community when they cough, sneeze, talk or breathe. If a face mask is unavailable, ill persons needing to go into the community should use a handkerchief or tissues to cover any coughing.
  • Persons in home isolation and their household members should be given infection control instructions: including frequent hand washing with soap and water.Use alcohol-based hand gels (containing at least 60% alcohol) when soap and water are not available and hands are not visibly dirty. When the ill person is within 6 feet of others at home, the ill person should wear a face mask if one is available and the ill person is able to tolerate wearing it.

Regarding Household Contacts:

  • Household contacts who are well should:
    1. remain home at the earliest sign of illness;
    2. minimize contact in the community to the extent possible;
    3. designate a single household family member as the ill person’s caregiver to minimize interactions with asymptomatic persons.

School Dismissal and Childcare Facility*Closure:

  • Dismissal of students should be strongly considered in schools with a confirmed or a suspected case epidemiologically linked to a confirmed case.
  • Decisions regarding broader school dismissal within these communities should be left to local authorities, taking into account the extent of ILI in the community.
  • If the school dismisses students or a childcare facility closes, they should also cancel all school or childcare related gatherings and encourage parents and students to avoid congregating outside of the school.
  • Schools and childcare facilities should dismiss students for a time period to be evaluated on an ongoing basis depending upon epidemiological findings.
  • Schools and childcare facilities should consult with their local or state health departments for guidance on reopening.If no additional confirmed or suspected cases are identified among students (or school-based personnel) for a period of 7 days, schools may consider reopening.
  • Schools and childcare facilities in unaffected areas should begin to prepare for the possibility of school dismissal or childcare facility closure. This includes asking teachers, parents and officials in charge of critical school-associated programs (such as meal services) to make contingency plans.

Other Social Distancing Interventions:

  • Large gatherings linked to settings or institutions with laboratory-confirmed cases should be cancelled, for example a school event linked to a school with cases;other large gatherings in the community may not need to be cancelled at this time.
  • Additional social distancing measures are currently not recommended.
  • Persons with underlying medical conditions who are at high risk for complications of influenza may wish to consider avoiding large gatherings.

These recommendations are subject to change as additional epidemiological and clinical data become available.

*Childcare facility: centers and facilities that provide care to any number of children in a nonresidential setting, large family childcare homes that provide care for seven or more children in the home of the provider and small family childcare homes that provide care to six or fewer children in the home of the provider.

To read the entire article click here: http://www.cdc.gov/swineflu/mitigation.htm

April 29, 2009

THE CHALLENGE OF FLU

April 29, 2009
 
The challenge of flu

Among threats to public health, influenza poses an unusual challenge. People, pigs, birds and horses have developed unique strains of flu, which can easily mix and match into new ones that the human immune system is ill-equipped to recognize.

And because the eight genes that form all Type A flu viruses -- the most dangerous kind -- are made of RNA instead of DNA, they don't copy themselves reliably and are prone to further mutation.

Flu research has accelerated since the Asian bird flu spread to humans in 1997. But the more scientists study it, the more questions they have.

"I know less about influenza today than I did 10 years ago," said Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota.

Yet for all its destructive power, the influenza virus is a straightforward organism.

Its outer shell is studded with a protein called hemagglutinin that allows flu particles to attach to cells lining the respiratory tract. The virus then takes over the host cell and uses it to make hundreds of copies. Those new flu particles use another surface protein, neuraminidase, to break off from the host so they can search for new targets.

There are 16 types of hemagglutinin, or H, and nine of neuraminidase, or N; the combination gives a flu strain its name. The swine flu involved in this outbreak is an H1N1 variety.

Scientists surmise that influenza originated in wild birds because they carry all types of H and N. Over thousands of years, the flu evolved into five major lineages, Olsen said -- one each for humans, pigs and horses, and two for birds.

The swine strains

Swine flus were first detected in the 1930s, but pigs have probably had their own strains for hundreds of years, said Greg Gray, director of the Center for Emerging Infectious Diseases at the University of Iowa College of Public Health.

For a long time, swine flu was the suspected culprit in the 1918 Spanish flu pandemic that killed about 50 million people. Scientists now blame a bird flu strain, which probably infected pigs and humans simultaneously, Gray said.
 
The pandemics of 1957 and 1968 involved strains that contained a mixture of human and avian flu viruses. Experts theorize that pigs were the mixing vessel in those cases, "but there's no smoking gun to indicate that," Olsen said.

Swine flu infected 200 people in 1976, including four soldiers at Ft. Dix, N.J., one of whom died. The virus circulated for about a month, then vanished as mysteriously as it came, according to the U.S. Centers for Disease Control and Prevention in Atlanta.
 
In 1988, a healthy 32-year-old women who visited a pig exhibit at a county fair came down with pneumonia and died eight days later. Epidemiologists tested the exhibitors and found that 76% of them had swine flu antibodies, a sign that their immune systems had tangled with the virus, according to the CDC.

The agency typically reports a case of swine flu in humans once every year or two. But from December 2005 to February 2009, it documented 12 U.S. cases.
 
Mexico is hardest hit: The government there has confirmed 22 deaths in patients with the virus, and a total of 103 deaths and 1,614 infections may be linked to swine flu.

Experts don't know why the flu is more virulent south of the border. Perhaps the genetic code of the Mexican version is slightly different, Olsen said.

"It can take as little as a single amino acid change to have a substantial difference in pathogenicity," he said.

Mexicans may have had longer exposure to the virus, and patients there may also be more vulnerable to secondary infections, such as pneumonia.

Cases go unreported

The World Health Organization estimates that swine flu is fatal in 1% to 4% of cases. But so many mild cases of infection go unreported that it's impossible to know its true virulence, experts said.

In fact, it may not be all that rare. A 2007 study in the journal Emerging Infectious Diseases compared swine flu exposure in farmers, their spouses and a control group of university students, faculty and staff.

Compared with the control group, the farmers were 55 times more likely to have swine flu antibodies, and the spouses were 28 times more likely.

"There are probably a lot of infections that are totally missed from the medical system," said Gray, who led the study.

Scientists are using samples of the new swine flu strain to infect laboratory animals, including mice, guinea pigs, ferrets and primates. Researchers will test whether direct contact is necessary for transmission and whether small flu droplets can spread easily from cage to cage. Those tests will provide clues about how easily the virus spreads and how deadly it is, Gray said.

"We don't know what this virus will do," Osterholm said. "It could burn itself out in the next four to six weeks and we never see it again. It could burn itself out over a more extended period of time."

But he said health officials can't ignore the chance that it could sputter out in the spring and reappear in late summer with a vengeance, as happened in 1918.


FACE MASK

Do face masks help prevent swine flu infection?

Many people in Mexico City, as well as travelers to and from Los Angeles, have been seen wearing mouth and nose protection of one kind or another in recent days. Face mask shouldn't replace other precautions.

Most were wearing face masks, which are loose-fitting and designed largely to help stop droplets from spreading from the person wearing the mask. They also protect the wearer's mouth and nose from splashes. They are not created to protect the wearer from breathing in very small particles.

If used correctly, masks and - more likely - respirators may indeed reduce the risk of getting influenza, according to information released from the CDC. But for people who live in areas with confirmed cases, there is no single action that will provide complete protection. It simply isn't practical to wear a mask all the time, and they are not 100% foolproof.

Face masks and respirators are most useful for people who are in crowded settings, such as classrooms or airplanes, where they will protect the mouth and nose from germs and reduce the likelihood of coughing or sneezing on other people.

Face masks and respirators are sometimes recommended for people who are in close contact with an infected person. "Close contact" is defined as three feet or less by the World Health Organization and six feet or less by the U.S. Occupational Safety and Health Administration.

Face masks and respirators should be worn once, according to the World Health Organization. (Look for face masks labeled for surgical, dental, medical procedure, isolation or laser use.)

Health experts note that face masks and respirators should be used along with other precautions, such as frequent hand-washing, covering coughs, staying at home if ill and avoiding crowds.

For more information on face masks and respirators, see these Web pages from the CDC:

www.cdc.gov/flu/professionals/infectioncontrol/maskguidance.htm

www.cdc.gov/Features/MasksRespirators/

www.cdc.gov/swineflu/masks.htm

SOME ADDITIONAL SWINE INFLUENZA RESOURCES

(1) CDC web site: http://www.cdc.gov/swineflu/?s_cid=swineFlu_outbreak_001

(2) Higher Education H1N1 Map Available

This map reflects the presence of the H1N1 Influenza virus on higher education, college and university campuses only.

This map is created with information shared with the Disaster Resilient Universities list serve (DRU) operated by the International Association of Emergency Managers - Universities and Colleges Committee (IAEM-UCC).

Please visit http://tinyurl.com/HigherEdH1N1Map to view the map.

(3 Center For Infectious Disease Research and Policy

http://www.cidrap.umn.edu/index.html

(4) APA Help Center: "Managing Your Anxiety about Swine Flu"

The American Psychological Association (APA) is providing information on H1N1 virus and how to deal with the stress and anxiety related to the virus. Please visit http://apahelpcenter.org/articles/article.php?id=194 for more information.

(5) http://news.health.com/2009/04/28/swine-flu-cases-hospitalized/